A prognostic approach towards Type 2 Diabetic Retinopathy-Scientific Conference Bangalore
Type 2 Diabetic retinopathy (T2DR) is a serious sight-threatening disease and the leading cause of blindness among people with diabetes. MicroRNAs are small non-coding RNA molecules which play a key role in controlling gene expression and certain biological processes. Studies show that dysregulation of microRNAs may lead to various diseases including T2DR, and thus, may be useful biomarkers for disease detection. Therefore, identifying biomarkers like microRNAs as a tool for the early and specific detection of T2DR, have great potential for diagnostic purposes.
Diversity of gut microbiota in autism reveals differential abundance of various bacterial species-CME medical conference 2017
TGut microbiome play an important role in early development and predisposition to disease. Gut-Brain axis provides bidirectional communicational route; imbalance of which can have pathophysiological consequences. Various factors play a role in the development of the gut microbiome. Gut dysbiosis is a frontier in autism research and affects 85% of autistic children (NIH report). Their microbiome typically has few overall microbes and smaller number of health promising microbes than their neurotypical peers. In view of this we have made an attempt to check the hypothesis that the gut microbes affect the brain thus altering the behaviour of an individual.
When Genomics and Personalised Medicine Meet “Tiny” Theranostics: Policy Concerns-personalised medicine conference 2017
Recent years have seen great strides being made in the “tiny” domains of microsurgery and nanomedical research and interventions (Leary 2006; Good, Monteiro, Skwarczynski and Toth 2014; Bagchi 2017; Caster, Patel, Zhang and Wang 2017; Mixson 2017). The establishment of links between genetics and personalised medicine dates back by several decades (Anderson 1985, 1988; Buchanan, Brock, Daniels and Wikler 2001; Gert, Culver and Clouser 2006), following the seminal discoveries relating to molecular genetics (Watson 1965; Sundar Rajan 2003/2016).
Diversity of gut microbiota in autism reveals differential abundance of various bacterial species-personalised medicine conference 2017
Gut microbiome play an important role in early development and predisposition to disease. Gut-Brain axis provides bidirectional communicational route; imbalance of which can have pathophysiological consequences. Various factors play a role in the development of the gut microbiome. Gut dysbiosis is a frontier in autism research and affects 85% of autistic children (NIH report).
Thiomer Based Trans Mucosal Drug Delivery System for an Anti-Ulcer Drug- Scientific Conference 2017
Introduction: Esomeprazole magnesium trihydrate (EMT) is a proton pump inhibitor which is used for the treatment of Gastroesophageal Reflux Disease (GERD). EMT is highly unstable in the stomach and undergoes extensive hepatic
using thiolated chitosan as mucoadhesive first pass metabolism. To overcome the limitation, the present study was carried out to formulate bilayered patches of Esomeprazole for buccal delivery.
Correlation of genetic and epigenetic alterations with treatment outcome of concurrent chemoradiation treatment (CRT) in cervical cancer-medical conference in bangalore
The 2015 estimates of cervical cancer account for a total of 527,624 new cervical cancer cases and 265,672 deaths all around the world. Cervical cancer estimates among Indian women aged between 15 to 44 years was reported as 122,844 new cases of which 67,477 resulted in death. Polymorphic gene variants, mRNA expression and epigenetic alterations of genes may alter DNA repair capacity and influence cancer progression and clinical responses to chemoradiotherapy.
Genetic basis of primary immunodeficiency diseases at PGIMER, Chandigarh-Medical conferences in karnataka 2017
Primary immunodeficiency disease (PID) are a heterogeneous group of genetic disorders characterized by defect in different components of the innate or adaptive immune system. More than 400 single gene defects that have been identified till date in various PIDs and the list expands each passing year....
Concurrence of Disease Free Survival expectancy estimate of Trastuzumab in HER2- Positive Breast Cancer: Results from single centerretrospective data-Scientific conferences in Bangalore.
Trastuzumab is one of the personalized drugs approved over a decade ago to treat breast cancer patients based on HER-2 neu gene status (H+BCP). This approach of personalizing treatment is reported with better outcomes in terms of efficacy and survival. However, there is a paucity of data on Trastuzumab efficacy and safety in India population.